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SMILES: C[C@H]1NC(=O)O[C@H]1c1ccc(cc1)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM262174 (4'-[(4R,5S)-4-methyl-2-oxo-1,3- oxazolidin-5-yl]-2...) Show SMILES C[C@H]1NC(=O)O[C@H]1c1ccc(cc1)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.36	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
VIM-1 metallo-beta-lactamase (Klebsiella pneumoniae)	BDBM262174 (4'-[(4R,5S)-4-methyl-2-oxo-1,3- oxazolidin-5-yl]-2...) Show SMILES C[C@H]1NC(=O)O[C@H]1c1ccc(cc1)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O |r| Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.76	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Klebsiella pneumoniae)	BDBM262174 (4'-[(4R,5S)-4-methyl-2-oxo-1,3- oxazolidin-5-yl]-2...) Show SMILES C[C@H]1NC(=O)O[C@H]1c1ccc(cc1)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.637	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair