null

SMILES: NS(=O)(=O)c1cccc(-c2ccc(cc2)-c2nnn[nH]2)c1-c1nn[nH]n1

InChI Key: InChIKey=LHEFWGXHCXOHIO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM262223 (4'-(1H-tetrazol-5-yl)-2-(2H- tetrazol-5-yl)bipheny...) Show SMILES NS(=O)(=O)c1cccc(-c2ccc(cc2)-c2nnn[nH]2)c1-c1nn[nH]n1 Show InChI InChI=1S/C14H11N9O2S/c15-26(24,25)11-3-1-2-10(12(11)14-18-22-23-19-14)8-4-6-9(7-5-8)13-16-20-21-17-13/h1-7H,(H2,15,24,25)(H,16,17,20,21)(H,18,19,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48.7	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
VIM-1 metallo-beta-lactamase (Klebsiella pneumoniae)	BDBM262223 (4'-(1H-tetrazol-5-yl)-2-(2H- tetrazol-5-yl)bipheny...) Show SMILES NS(=O)(=O)c1cccc(-c2ccc(cc2)-c2nnn[nH]2)c1-c1nn[nH]n1 Show InChI InChI=1S/C14H11N9O2S/c15-26(24,25)11-3-1-2-10(12(11)14-18-22-23-19-14)8-4-6-9(7-5-8)13-16-20-21-17-13/h1-7H,(H2,15,24,25)(H,16,17,20,21)(H,18,19,22,23)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.2	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Klebsiella pneumoniae)	BDBM262223 (4'-(1H-tetrazol-5-yl)-2-(2H- tetrazol-5-yl)bipheny...) Show SMILES NS(=O)(=O)c1cccc(-c2ccc(cc2)-c2nnn[nH]2)c1-c1nn[nH]n1 Show InChI InChI=1S/C14H11N9O2S/c15-26(24,25)11-3-1-2-10(12(11)14-18-22-23-19-14)8-4-6-9(7-5-8)13-16-20-21-17-13/h1-7H,(H2,15,24,25)(H,16,17,20,21)(H,18,19,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.637	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair