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SMILES: Nc1nc2c(cccc2s1)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O

InChI Key: InChIKey=HUXHHCLIJZRUQT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM262282 (3-(2-aminobenzo[d]thiazol- 4-yl)-2-(1H-tetrazol-5-...) Show SMILES Nc1nc2c(cccc2s1)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O Show InChI InChI=1S/C14H11N7O2S2/c15-14-17-12-8(4-1-5-9(12)24-14)7-3-2-6-10(25(16,22)23)11(7)13-18-20-21-19-13/h1-6H,(H2,15,17)(H2,16,22,23)(H,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.6	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
VIM-1 metallo-beta-lactamase (Klebsiella pneumoniae)	BDBM262282 (3-(2-aminobenzo[d]thiazol- 4-yl)-2-(1H-tetrazol-5-...) Show SMILES Nc1nc2c(cccc2s1)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O Show InChI InChI=1S/C14H11N7O2S2/c15-14-17-12-8(4-1-5-9(12)24-14)7-3-2-6-10(25(16,22)23)11(7)13-18-20-21-19-13/h1-6H,(H2,15,17)(H2,16,22,23)(H,18,19,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.1	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Klebsiella pneumoniae)	BDBM262282 (3-(2-aminobenzo[d]thiazol- 4-yl)-2-(1H-tetrazol-5-...) Show SMILES Nc1nc2c(cccc2s1)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O Show InChI InChI=1S/C14H11N7O2S2/c15-14-17-12-8(4-1-5-9(12)24-14)7-3-2-6-10(25(16,22)23)11(7)13-18-20-21-19-13/h1-6H,(H2,15,17)(H2,16,22,23)(H,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair