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SMILES: Cc1cccn2c(cnc12)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O

InChI Key: InChIKey=HZPJCVFFDAMKRH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM262287 (3-(8-methylimidazo[1,2-a] pyridin-3-yl)-2-(1H- tet...) Show SMILES Cc1cccn2c(cnc12)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O Show InChI InChI=1S/C15H13N7O2S/c1-9-4-3-7-22-11(8-17-15(9)22)10-5-2-6-12(25(16,23)24)13(10)14-18-20-21-19-14/h2-8H,1H3,(H2,16,23,24)(H,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	98.4	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
VIM-1 metallo-beta-lactamase (Klebsiella pneumoniae)	BDBM262287 (3-(8-methylimidazo[1,2-a] pyridin-3-yl)-2-(1H- tet...) Show SMILES Cc1cccn2c(cnc12)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O Show InChI InChI=1S/C15H13N7O2S/c1-9-4-3-7-22-11(8-17-15(9)22)10-5-2-6-12(25(16,23)24)13(10)14-18-20-21-19-14/h2-8H,1H3,(H2,16,23,24)(H,18,19,20,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.78	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Klebsiella pneumoniae)	BDBM262287 (3-(8-methylimidazo[1,2-a] pyridin-3-yl)-2-(1H- tet...) Show SMILES Cc1cccn2c(cnc12)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O Show InChI InChI=1S/C15H13N7O2S/c1-9-4-3-7-22-11(8-17-15(9)22)10-5-2-6-12(25(16,23)24)13(10)14-18-20-21-19-14/h2-8H,1H3,(H2,16,23,24)(H,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.637	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair