null

SMILES: NC(=O)c1nccc2cc(ccc12)-c1cccc(c1-c1nn[nH]n1)S(N)(=O)=O

InChI Key: InChIKey=BMTFZBSAMOYHLW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM262429 (6-(3-sulfamoyl-2-(2H-tetrazol-5-yl)phenyl)isoquino...) Show SMILES NC(=O)c1nccc2cc(ccc12)-c1cccc(c1-c1nn[nH]n1)S(N)(=O)=O Show InChI InChI=1S/C17H13N7O3S/c18-16(25)15-12-5-4-9(8-10(12)6-7-20-15)11-2-1-3-13(28(19,26)27)14(11)17-21-23-24-22-17/h1-8H,(H2,18,25)(H2,19,26,27)(H,21,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42.9	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
VIM-1 metallo-beta-lactamase (Klebsiella pneumoniae)	BDBM262429 (6-(3-sulfamoyl-2-(2H-tetrazol-5-yl)phenyl)isoquino...) Show SMILES NC(=O)c1nccc2cc(ccc12)-c1cccc(c1-c1nn[nH]n1)S(N)(=O)=O Show InChI InChI=1S/C17H13N7O3S/c18-16(25)15-12-5-4-9(8-10(12)6-7-20-15)11-2-1-3-13(28(19,26)27)14(11)17-21-23-24-22-17/h1-8H,(H2,18,25)(H2,19,26,27)(H,21,22,23,24)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.2	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Klebsiella pneumoniae)	BDBM262429 (6-(3-sulfamoyl-2-(2H-tetrazol-5-yl)phenyl)isoquino...) Show SMILES NC(=O)c1nccc2cc(ccc12)-c1cccc(c1-c1nn[nH]n1)S(N)(=O)=O Show InChI InChI=1S/C17H13N7O3S/c18-16(25)15-12-5-4-9(8-10(12)6-7-20-15)11-2-1-3-13(28(19,26)27)14(11)17-21-23-24-22-17/h1-8H,(H2,18,25)(H2,19,26,27)(H,21,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.342	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair