BDBM262687 3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(piperidin-4-yl)ethyl)-2-(2H- tetrazol-5-yl)benzenesulfonamide::US9708336, 540

SMILES: Nc1nc2c(cccc2s1)-c1ccc(CCC2CCNCC2)c(c1-c1nn[nH]n1)S(N)(=O)=O

InChI Key: InChIKey=AJTQAFXTVVRQHU-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262687   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM262687 (3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(piperidin-4...) Show SMILES Nc1nc2c(cccc2s1)-c1ccc(CCC2CCNCC2)c(c1-c1nn[nH]n1)S(N)(=O)=O Show InChI InChI=1S/C21H24N8O2S2/c22-21-25-18-15(2-1-3-16(18)32-21)14-7-6-13(5-4-12-8-10-24-11-9-12)19(33(23,30)31)17(14)20-26-28-29-27-20/h1-3,6-7,12,24H,4-5,8-11H2,(H2,22,25)(H2,23,30,31)(H,26,27,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.8	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
Beta-lactamase VIM-1 (Klebsiella pneumoniae)	BDBM262687 (3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(piperidin-4...) Show SMILES Nc1nc2c(cccc2s1)-c1ccc(CCC2CCNCC2)c(c1-c1nn[nH]n1)S(N)(=O)=O Show InChI InChI=1S/C21H24N8O2S2/c22-21-25-18-15(2-1-3-16(18)32-21)14-7-6-13(5-4-12-8-10-24-11-9-12)19(33(23,30)31)17(14)20-26-28-29-27-20/h1-3,6-7,12,24H,4-5,8-11H2,(H2,22,25)(H2,23,30,31)(H,26,27,28,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
Beta-lactamase NDM-1 (Klebsiella pneumoniae)	BDBM262687 (3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(piperidin-4...) Show SMILES Nc1nc2c(cccc2s1)-c1ccc(CCC2CCNCC2)c(c1-c1nn[nH]n1)S(N)(=O)=O Show InChI InChI=1S/C21H24N8O2S2/c22-21-25-18-15(2-1-3-16(18)32-21)14-7-6-13(5-4-12-8-10-24-11-9-12)19(33(23,30)31)17(14)20-26-28-29-27-20/h1-3,6-7,12,24H,4-5,8-11H2,(H2,22,25)(H2,23,30,31)(H,26,27,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.199	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair