BDBM262997 N-(5H-chromeno[3,4-c]pyridin-8-yl)-3-isopropylpiperidine-2-carboxamide::US9708337, 10
SMILES: CC(C)C1CCCNC1C(=O)Nc1ccc-2c(OCc3cnccc-23)c1
InChI Key: InChIKey=FWJOCWBMXPURGY-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM262997 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-3-isopropylpipe...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra... | US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9 | |||||||||||
More data for this Ligand-Target Pair |