BDBM2631 3-(1,4-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::Bisindolylmaleimide deriv. 53

SMILES: Cc1cccc2n(C)cc(C3=C(C(=O)NC3=O)c3cn(C)c4ccccc34)c12

InChI Key: InChIKey=XZTXSLFLRRWEIH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM2631 (3-(1,4-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indo...) Show SMILES Cc1cccc2n(C)cc(C3=C(C(=O)NC3=O)c3cn(C)c4ccccc34)c12 |t:10| Show InChI InChI=1S/C23H19N3O2/c1-13-7-6-10-18-19(13)16(12-26(18)3)21-20(22(27)24-23(21)28)15-11-25(2)17-9-5-4-8-14(15)17/h4-12H,1-3H3,(H,24,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair
Protein Kinase C (Rattus norvegicus (rat))	BDBM2631 (3-(1,4-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indo...) Show SMILES Cc1cccc2n(C)cc(C3=C(C(=O)NC3=O)c3cn(C)c4ccccc34)c12 |t:10| Show InChI InChI=1S/C23H19N3O2/c1-13-7-6-10-18-19(13)16(12-26(18)3)21-20(22(27)24-23(21)28)15-11-25(2)17-9-5-4-8-14(15)17/h4-12H,1-3H3,(H,24,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair