BDBM26340 (2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{3-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]propyl}-4-methylpentanamide::Peptide analogue, 20
SMILES: CC(C)C[C@H](CCCNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(F)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
InChI Key: InChIKey=JTRIMPIOJZGKFB-XWRHLKSWSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G-protein Coupled Receptor 54 (Homo sapiens (Human)) | BDBM26340 ((2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | 7.3 | 25 |
Kyoto University | Assay Description Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut... | J Med Chem 51: 7645-9 (2008) Article DOI: 10.1021/jm800930w BindingDB Entry DOI: 10.7270/Q2ZS2TTP | |||||||||||
More data for this Ligand-Target Pair |