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BDBM2639 (Phenylindolyl)maleimide deriv. 61::3-(1-methyl-1H-indol-3-yl)-4-[4-(methylsulfanyl)phenyl]-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES: CSc1ccc(cc1)C1=C(C(=O)NC1=O)c1cn(C)c2ccccc12

InChI Key: InChIKey=AYZKBILFOZHAJJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2639   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Kinase C


(Rattus norvegicus (rat))
BDBM2639
PNG
((Phenylindolyl)maleimide deriv. 61 | 3-(1-methyl-1...)
Show SMILES CSc1ccc(cc1)C1=C(C(=O)NC1=O)c1cn(C)c2ccccc12 |t:9|
Show InChI InChI=1S/C20H16N2O2S/c1-22-11-15(14-5-3-4-6-16(14)22)18-17(19(23)21-20(18)24)12-7-9-13(25-2)10-8-12/h3-11H,1-2H3,(H,21,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Roche Products Limited



Assay Description
The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...


J Med Chem 35: 177-84 (1992)


Article DOI: 10.1016/j.bmc.2005.03.050
BindingDB Entry DOI: 10.7270/Q2K64G8V
More data for this
Ligand-Target Pair