null
SMILES: COc1ccn(-c2ccc(cc2)N2CCN(CCCc3c[nH]c4ccc(cc34)C#N)CC2)c(=O)c1
InChI Key: InChIKey=UXYBQHAMKCVWPG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM264109 (3-(3-(4-(4-(4-methoxy-2-oxopyridin-1(2H)-yl)phenyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
SUNSHINE LAKE PHARMA CO., LTD. US Patent | Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o... | US Patent US9714232 (2017) BindingDB Entry DOI: 10.7270/Q28054N5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM264109 (3-(3-(4-(4-(4-methoxy-2-oxopyridin-1(2H)-yl)phenyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM264109 (3-(3-(4-(4-(4-methoxy-2-oxopyridin-1(2H)-yl)phenyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | 7.4 | n/a |
SUNSHINE LAKE PHARMA CO., LTD. US Patent | Assay Description The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc... | US Patent US9714232 (2017) BindingDB Entry DOI: 10.7270/Q28054N5 | |||||||||||
More data for this Ligand-Target Pair |