BindingDB PrimarySearch

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SMILES: O=c1n(ccc2occc12)-c1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1

InChI Key: InChIKey=RLGFCRXXEKJBKA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 264120
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM264120 (3-(4-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.140	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22� C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...				US Patent US9714232 (2017) BindingDB Entry DOI: 10.7270/Q28054N5
SUNSHINE LAKE PHARMA CO., LTD. US Patent					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM264120 (3-(4-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM264120 (3-(4-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM264120 (3-(4-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens)	BDBM264120 (3-(4-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM264120 (3-(4-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	7.4	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The synaptosomes (150 μg) prepared from a rat brain were incubated at 37� C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...				US Patent US9714232 (2017) BindingDB Entry DOI: 10.7270/Q28054N5
SUNSHINE LAKE PHARMA CO., LTD. US Patent					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM264120 (3-(4-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair