BDBM264270 6-(2-Chlorophenyl)-2-((3-methyl-4-(piperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one::US9714244, 24

SMILES: Cc1cc(Nc2ncc3c(ccn(-c4ccccc4Cl)c3=O)n2)ccc1N1CCNCC1

InChI Key: InChIKey=ASMSMKQXDUFHOC-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Wee1-like protein kinase (Homo sapiens (Human))	BDBM264270 (6-(2-Chlorophenyl)-2-((3-methyl-4-(piperazin-1-yl)...) Show SMILES Cc1cc(Nc2ncc3c(ccn(-c4ccccc4Cl)c3=O)n2)ccc1N1CCNCC1 Show InChI InChI=1S/C24H23ClN6O/c1-16-14-17(6-7-21(16)30-12-9-26-10-13-30)28-24-27-15-18-20(29-24)8-11-31(23(18)32)22-5-3-2-4-19(22)25/h2-8,11,14-15,26H,9-10,12-13H2,1H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	25
ALMAC DISCOVERY LIMITED US Patent					Assay Description In the measurement of Wee-1 activity, a commercial peptide Poly(Lys Tyr(4:1)) hydrobromide was purchased from Sigma Aldrich and used as the substrate...				US Patent US9714244 (2017) BindingDB Entry DOI: 10.7270/Q2GH9KZ4
					More data for this Ligand-Target Pair