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BDBM2646 (Phenylindolyl)maleimide deriv. 68::3-(1-methyl-1H-indol-3-yl)-4-(3-phenoxyphenyl)-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2cccc(Oc3ccccc3)c2)c2ccccc12

InChI Key: InChIKey=OZFYUTLSPUDXNO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2646   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Kinase C


(Rattus norvegicus (rat))
BDBM2646
PNG
((Phenylindolyl)maleimide deriv. 68 | 3-(1-methyl-1...)
Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cccc(Oc3ccccc3)c2)c2ccccc12 |t:4|
Show InChI InChI=1S/C25H18N2O3/c1-27-15-20(19-12-5-6-13-21(19)27)23-22(24(28)26-25(23)29)16-8-7-11-18(14-16)30-17-9-3-2-4-10-17/h2-15H,1H3,(H,26,28,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Roche Products Limited



Assay Description
The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...


J Med Chem 35: 177-84 (1992)


Article DOI: 10.1016/j.bmc.2005.03.050
BindingDB Entry DOI: 10.7270/Q2K64G8V
More data for this
Ligand-Target Pair