BDBM264627 US9718760, C160

SMILES: Oc1ccc(cc1O)S(=O)(=O)NCc1ccccc1

InChI Key: InChIKey=PWUHSENCXPKXKJ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 264627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PAI-1/uPA (Homo sapiens (Human))	BDBM264627 (US9718760, C160) Show SMILES Oc1ccc(cc1O)S(=O)(=O)NCc1ccccc1 Show InChI InChI=1S/C13H13NO4S/c15-12-7-6-11(8-13(12)16)19(17,18)14-9-10-4-2-1-3-5-10/h1-8,14-16H,9H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
ATIII/alphaIIa (Homo sapiens (Human))	BDBM264627 (US9718760, C160) Show SMILES Oc1ccc(cc1O)S(=O)(=O)NCc1ccccc1 Show InChI InChI=1S/C13H13NO4S/c15-12-7-6-11(8-13(12)16)19(17,18)14-9-10-4-2-1-3-5-10/h1-8,14-16H,9H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.33E+6	n/a	n/a	n/a	n/a	n/a	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
PAI-1/tPA (Homo sapiens (Human))	BDBM264627 (US9718760, C160) Show SMILES Oc1ccc(cc1O)S(=O)(=O)NCc1ccccc1 Show InChI InChI=1S/C13H13NO4S/c15-12-7-6-11(8-13(12)16)19(17,18)14-9-10-4-2-1-3-5-10/h1-8,14-16H,9H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.82E+4	n/a	n/a	n/a	n/a	n/a	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair