BDBM26475 2-N,4-N-bis(3-bromophenyl)-5-fluoropyrimidine-2,4-diamine::pyrimidine, 1
SMILES: Fc1cnc(Nc2cccc(Br)c2)nc1Nc1cccc(Br)c1
InChI Key: InChIKey=JMFBVEWGVFCOKD-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM26475 (2-N,4-N-bis(3-bromophenyl)-5-fluoropyrimidine-2,4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | 7.5 | 22 |
GSK | Assay Description The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium... | J Med Chem 51: 4632-40 (2008) Article DOI: 10.1021/jm800566m BindingDB Entry DOI: 10.7270/Q26971XR | |||||||||||
More data for this Ligand-Target Pair |