BDBM2649 (Phenylindolyl)maleimide deriv. 71::3-(1-methyl-1H-indol-3-yl)-4-[3-(trifluoromethyl)phenyl]-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2cccc(c2)C(F)(F)F)c2ccccc12

InChI Key: InChIKey=IHTJAOYORDQOPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2649   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Kinase C (Rattus norvegicus (rat))	BDBM2649 ((Phenylindolyl)maleimide deriv. 71 | 3-(1-methyl-1...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cccc(c2)C(F)(F)F)c2ccccc12 |t:4| Show InChI InChI=1S/C20H13F3N2O2/c1-25-10-14(13-7-2-3-8-15(13)25)17-16(18(26)24-19(17)27)11-5-4-6-12(9-11)20(21,22)23/h2-10H,1H3,(H,24,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair