BDBM265118 US9718790, I-1717

SMILES: CCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccnc(c3)C(=O)NC)cc2)n(Cc2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=IMIAZSYJRAXFLG-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 265118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM265118 (US9718790, I-1717) Show SMILES CCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccnc(c3)C(=O)NC)cc2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C25H23ClN6O4/c1-3-31-24(34)30-23(32(25(31)35)15-16-4-6-17(26)7-5-16)29-18-8-10-19(11-9-18)36-20-12-13-28-21(14-20)22(33)27-2/h4-14H,3,15H2,1-2H3,(H,27,33)(H,29,30,34)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
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