BDBM2655 (Phenylindolyl)maleimide deriv. 77::3-(2,5-dimethylphenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES: Cc1ccc(C)c(c1)C1=C(C(=O)NC1=O)c1cn(C)c2ccccc12

InChI Key: InChIKey=AJAGWKXGNBDGDQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM2655 ((Phenylindolyl)maleimide deriv. 77 | 3-(2,5-dimeth...) Show SMILES Cc1ccc(C)c(c1)C1=C(C(=O)NC1=O)c1cn(C)c2ccccc12 |t:9| Show InChI InChI=1S/C21H18N2O2/c1-12-8-9-13(2)15(10-12)18-19(21(25)22-20(18)24)16-11-23(3)17-7-5-4-6-14(16)17/h4-11H,1-3H3,(H,22,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair
Protein Kinase C (Rattus norvegicus (rat))	BDBM2655 ((Phenylindolyl)maleimide deriv. 77 | 3-(2,5-dimeth...) Show SMILES Cc1ccc(C)c(c1)C1=C(C(=O)NC1=O)c1cn(C)c2ccccc12 |t:9| Show InChI InChI=1S/C21H18N2O2/c1-12-8-9-13(2)15(10-12)18-19(21(25)22-20(18)24)16-11-23(3)17-7-5-4-6-14(16)17/h4-11H,1-3H3,(H,22,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair