BDBM26613 (2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-enoic acid::Compound 13778

SMILES: OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O

InChI Key: InChIKey=ZTQRMGDLUGQTTF-MNPOOLNOSA-L

Data: 2 KI  11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 26613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
phosphatase Cdc25 (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged Cdc25a catalytic domain expressed in Escherichia coli BL21(DE3) using 3-O-Methylfluorescein phosphate as substrat...				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	369	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged Cdc25b catalytic domain expressed in Escherichia coli BL21(DE3) using 3-O-Methylfluorescein phosphate as substrat...				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged VHR using 3-O-Methylfluorescein phosphate as substrate incubated for 10 mins prior to substrate addition b...				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase beta (PTPβ) (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of PTP-beta receptor using 3-O-Methylfluorescein phosphate as substrate incubated for 10 mins prior to substrate addition by fluorometry				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of MKP3 using 3-O-Methylfluorescein phosphate as substrate incubated for 10 mins prior to substrate addition by fluorometry				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of PTP1B using 3-O-Methylfluorescein phosphate as substrate incubated for 10 mins prior to substrate addition by fluorometry				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of PTPMT1 using 3-O-Methylfluorescein phosphate as substrate incubated for 10 mins prior to substrate addition by fluorometry				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase beta (PTPβ) (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of PTP-beta receptor using para-nitrophenol as substrate by colorimetric analysis				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
phosphatase Cdc25 (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged Cdc25a catalytic domain expressed in Escherichia coli BL21(DE3) using 3-O-Methylfluorescein phosphate as substrat...				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged Cdc25b catalytic domain expressed in Escherichia coli BL21(DE3) using 3-O-Methylfluorescein phosphate as substrat...				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
Cdc25C (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged Cdc25c catalytic domain expressed in Escherichia coli BL21(DE3) using 3-O-Methylfluorescein phosphate as substrat...				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair
Apurinic-apyrimidinic endonuclease 1 (APE-1) (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.5	22
The Johns Hopkins University					Assay Description The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...				Mol Pharmacol 73: 669-77 (2008) Article DOI: 10.1124/mol.107.042622 BindingDB Entry DOI: 10.7270/Q2WS8RJX
					More data for this Ligand-Target Pair
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (Homo sapiens (Human))	BDBM26613 ((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...) Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of human PTEN using 3-O-Methylfluorescein phosphate as substrate incubated for 10 mins prior to substrate addition by fluorometry				Bioorg Med Chem 20: 4371-6 (2012) Article DOI: 10.1016/j.bmc.2012.05.040 BindingDB Entry DOI: 10.7270/Q2RB75N4
					More data for this Ligand-Target Pair