BDBM266378 US9718790, I-2230

SMILES: CCCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccc(nc3)C#N)cc2)n(Cc2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=UVUKXDJEOZGJHQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 266378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM266378 (US9718790, I-2230) Show SMILES CCCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccc(nc3)C#N)cc2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C25H21ClN6O3/c1-2-13-31-24(33)30-23(32(25(31)34)16-17-3-5-18(26)6-4-17)29-19-7-10-21(11-8-19)35-22-12-9-20(14-27)28-15-22/h3-12,15H,2,13,16H2,1H3,(H,29,30,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair