BindingDB logo
myBDB logout

null

SMILES: CCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccnc(c3)C(=O)NC)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=DLHJALRVLVWQSF-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 266698   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))		BDBM266698
PNG
(US9718790, I-2432)
Show SMILES CCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccnc(c3)C(=O)NC)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C25H22ClFN6O4/c1-3-32-24(35)31-23(33(25(32)36)14-15-4-6-16(26)7-5-15)30-17-8-9-21(19(27)12-17)37-18-10-11-29-20(13-18)22(34)28-2/h4-13H,3,14H2,1-2H3,(H,28,34)(H,30,31,35)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/a7.5n/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...

US Patent US9718790 (2017)


BindingDB Entry DOI: 10.7270/Q22809KB
More data for this
Ligand-Target Pair