BDBM266762 US9718790, I-2497

SMILES: CCn1c(=O)[nH]\c(=N/c2ccc(Oc3cccc(n3)C(N)=O)cc2)n(C[C@H]2CC[C@H](C)CC2)c1=O

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 266762   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM266762 (US9718790, I-2497) Show SMILES CCn1c(=O)[nH]\c(=N/c2ccc(Oc3cccc(n3)C(N)=O)cc2)n(C[C@H]2CC[C@H](C)CC2)c1=O |r,wU:26.27,wD:29.31,(7.34,,;6,.77,;4.67,,;3.33,.77,;3.33,2.31,;2,,;2,-1.54,;.67,-2.31,;-.67,-1.54,;-.67,,;-2,.77,;-3.33,,;-4.67,.77,;-4.67,2.31,;-3.33,3.08,;-3.33,4.62,;-4.67,5.39,;-6,4.62,;-6,3.08,;-7.34,5.39,;-8.67,4.62,;-7.34,6.93,;-3.33,-1.54,;-2,-2.31,;3.33,-2.31,;3.33,-3.85,;4.67,-4.62,;6,-3.85,;7.34,-4.62,;7.34,-6.16,;8.67,-6.93,;6,-6.93,;4.67,-6.16,;4.67,-1.54,;6,-2.31,)| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair