BDBM26701 7-chloro-9-ethyl-6-fluoro-1-methyl-1H,3H,4H,9H-quinolino[2,3-c][1,2]oxazole-3,4-dione::Isoxazoloquinolinedione, 9

SMILES: CCn1c2n(C)oc(=O)c2c(=O)c2cc(F)c(Cl)cc12

InChI Key: InChIKey=NKVRZICOCUNRHC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26701   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM26701 (7-chloro-9-ethyl-6-fluoro-1-methyl-1H,3H,4H,9H-qui...) Show SMILES CCn1c2n(C)oc(=O)c2c(=O)c2cc(F)c(Cl)cc12 Show InChI InChI=1S/C13H10ClFN2O3/c1-3-17-9-5-7(14)8(15)4-6(9)11(18)10-12(17)16(2)20-13(10)19/h4-5H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	50.1	-9.85	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...				Bioorg Med Chem Lett 18: 5206-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.079 BindingDB Entry DOI: 10.7270/Q2833QBF
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM26701 (7-chloro-9-ethyl-6-fluoro-1-methyl-1H,3H,4H,9H-qui...) Show SMILES CCn1c2n(C)oc(=O)c2c(=O)c2cc(F)c(Cl)cc12 Show InChI InChI=1S/C13H10ClFN2O3/c1-3-17-9-5-7(14)8(15)4-6(9)11(18)10-12(17)16(2)20-13(10)19/h4-5H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.42E+3	>-7.89	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...				Bioorg Med Chem Lett 18: 5206-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.079 BindingDB Entry DOI: 10.7270/Q2833QBF
					More data for this Ligand-Target Pair