BDBM267025 4-{[(4-Bromo-2,5-dichlorothiophen-3-yl)sulfonyl]amino}-2-hydroxybenzoic acid::US9718809, 22

SMILES: OC(=O)c1ccc(NS(=O)(=O)c2c(Cl)sc(Cl)c2Br)cc1O

InChI Key: InChIKey=AZGBLHROZQVKNV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (Homo sapiens (Human))	BDBM267025 (4-{[(4-Bromo-2,5-dichlorothiophen-3-yl)sulfonyl]am...) Show SMILES OC(=O)c1ccc(NS(=O)(=O)c2c(Cl)sc(Cl)c2Br)cc1O Show InChI InChI=1S/C11H6BrCl2NO5S2/c12-7-8(10(14)21-9(7)13)22(19,20)15-4-1-2-5(11(17)18)6(16)3-4/h1-3,15-16H,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kancera AB US Patent					Assay Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...				US Patent US9718809 (2017) BindingDB Entry DOI: 10.7270/Q28S4RXR
					More data for this Ligand-Target Pair