BDBM267035 2-Methoxyethyl 4-({[5-chloro-4-(2-hydroxyphenyl)-2-thienyl]sulfonyl}amino)-2-hydroxybenzoate::US9718809, 133

SMILES: COCCOC(=O)c1ccc(NS(=O)(=O)c2cc(c(Cl)s2)-c2ccccc2O)cc1O

InChI Key: InChIKey=ZWAAMALQVVSHIY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) (Homo sapiens (Human))	BDBM267035 (2-Methoxyethyl 4-({[5-chloro-4-(2-hydroxyphenyl)-2...) Show SMILES COCCOC(=O)c1ccc(NS(=O)(=O)c2cc(c(Cl)s2)-c2ccccc2O)cc1O Show InChI InChI=1S/C20H18ClNO7S2/c1-28-8-9-29-20(25)14-7-6-12(10-17(14)24)22-31(26,27)18-11-15(19(21)30-18)13-4-2-3-5-16(13)23/h2-7,10-11,22-24H,8-9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kancera AB US Patent					Assay Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...				US Patent US9718809 (2017) BindingDB Entry DOI: 10.7270/Q28S4RXR
					More data for this Ligand-Target Pair