BDBM267071 Methyl 4-[(biphenyl-3-ylsulfonyl)amino]-2-hydroxybenzoate::US9718809, 87

SMILES: COC(=O)c1ccc(NS(=O)(=O)c2cccc(c2)-c2ccccc2)cc1O

InChI Key: InChIKey=YNNMTBWFBJSNSD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267071   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (Homo sapiens (Human))	BDBM267071 (Methyl 4-[(biphenyl-3-ylsulfonyl)amino]-2-hydroxyb...) Show SMILES COC(=O)c1ccc(NS(=O)(=O)c2cccc(c2)-c2ccccc2)cc1O Show InChI InChI=1S/C20H17NO5S/c1-26-20(23)18-11-10-16(13-19(18)22)21-27(24,25)17-9-5-8-15(12-17)14-6-3-2-4-7-14/h2-13,21-22H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kancera AB US Patent					Assay Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...				US Patent US9718809 (2017) BindingDB Entry DOI: 10.7270/Q28S4RXR
					More data for this Ligand-Target Pair