BDBM267078 2-Methoxy-1-(methoxymethyl)ethyl 4-({[5-chloro-4-(3-fluorophenyl)-2-thienyl]sulfonyl}amino)-2-hydroxybenzoate::US9718809, 222

SMILES: COCC(COC)OC(=O)c1ccc(NS(=O)(=O)c2cc(c(Cl)s2)-c2cccc(F)c2)cc1O

InChI Key: InChIKey=TZTICUVEQBGJBK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267078   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (Homo sapiens (Human))	BDBM267078 (2-Methoxy-1-(methoxymethyl)ethyl 4-({[5-chloro-4-(...) Show SMILES COCC(COC)OC(=O)c1ccc(NS(=O)(=O)c2cc(c(Cl)s2)-c2cccc(F)c2)cc1O Show InChI InChI=1S/C22H21ClFNO7S2/c1-30-11-16(12-31-2)32-22(27)17-7-6-15(9-19(17)26)25-34(28,29)20-10-18(21(23)33-20)13-4-3-5-14(24)8-13/h3-10,16,25-26H,11-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kancera AB US Patent					Assay Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...				US Patent US9718809 (2017) BindingDB Entry DOI: 10.7270/Q28S4RXR
					More data for this Ligand-Target Pair