BDBM26728 N-[4-(1,3-benzothiazol-2-yl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-4-carboxamide::benzothiazole analogue, 16a
SMILES: O=C(Nc1ccc(cc1)-c1nc2ccccc2s1)C1CCN(CC1)S(=O)(=O)c1cccs1
InChI Key: InChIKey=AXEYTFGWEFGVSD-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM26728 (N-[4-(1,3-benzothiazol-2-yl)phenyl]-1-(thiophene-2...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Abbott Laboratories | Assay Description [3H]anandamide was incubated with membranes to produce radiolabeled ethanolamine and unlabeled arachidonic acid. Charcoal selectively binds anandamid... | J Med Chem 52: 170-80 (2009) Article DOI: 10.1021/jm801042a BindingDB Entry DOI: 10.7270/Q24B2ZMQ | |||||||||||
More data for this Ligand-Target Pair |