BDBM26733 N-{4-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]phenyl}-1-(thiophene-2-sulfonyl)piperidine-4-carboxamide::thiazole analogue, 17a
SMILES: COc1cccc(c1)-c1csc(n1)-c1ccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2cccs2)cc1
InChI Key: InChIKey=DZRVDGNBLXNIGK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM26733 (N-{4-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]phenyl}...) | PDB MMDB B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Abbott Laboratories | Assay Description [3H]anandamide was incubated with membranes to produce radiolabeled ethanolamine and unlabeled arachidonic acid. Charcoal selectively binds anandamid... | J Med Chem 52: 170-80 (2009) Article DOI: 10.1021/jm801042a BindingDB Entry DOI: 10.7270/Q24B2ZMQ | |||||||||||
More data for this Ligand-Target Pair |