BDBM267946 (3aR,5R,6S,7R,7aR)-5- ((cyclobutylamino)methyl)-2- (methylamino)-5,6,7,7a-tetrahydro- 3aH-pyrano[3,2-d]thiazole-6,7-diol::US9718854, 35

SMILES: CNC1=N[C@H]2[C@H](O[C@H](CNC3CCC3)[C@@H](O)[C@@H]2O)S1

InChI Key: InChIKey=BSOAIPRYKRRKGP-ISUQUUIWSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrodipicolinate synthase-like, mitochondrial (Homo sapiens (Human))	BDBM267946 ((3aR,5R,6S,7R,7aR)-5- ((cyclobutylamino)methyl)-2-...) Show SMILES CNC1=N[C@H]2[C@H](O[C@H](CNC3CCC3)[C@@H](O)[C@@H]2O)S1 |r,t:2| Show InChI InChI=1S/C12H21N3O3S/c1-13-12-15-8-10(17)9(16)7(18-11(8)19-12)5-14-6-3-2-4-6/h6-11,14,16-17H,2-5H2,1H3,(H,13,15)/t7-,8-,9-,10-,11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40	-12.1	n/a	n/a	n/a	n/a	n/a	7.0	25
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent					Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...				US Patent US9718854 (2017) BindingDB Entry DOI: 10.7270/Q2CJ8GH3
					More data for this Ligand-Target Pair