BDBM267947 (3aR,5R,6S,7R,7aR)-5- ((cyclopentylamino)methyl)-2- (methylamino)-5,6,7,7a-tetrahydro- 3aH-pyrano[3,2-d]thiazole-6,7-diol::US9718854, 37
SMILES: CNC1=N[C@H]2[C@H](O[C@H](CNC3CCCC3)[C@@H](O)[C@@H]2O)S1
InChI Key: InChIKey=WELRTUZMUOJQLV-LZQZFOIKSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrodipicolinate synthase-like, mitochondrial (Homo sapiens (Human)) | BDBM267947 ((3aR,5R,6S,7R,7aR)-5- ((cyclopentylamino)methyl)-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.600 | -12.6 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9718854 (2017) BindingDB Entry DOI: 10.7270/Q2CJ8GH3 | |||||||||||
More data for this Ligand-Target Pair |