BDBM26839 N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoylethyl)-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene]-5-(pyridin-3-yl)thiophene-2-carboxamide::acylated 2-aminobenzimidazole, 33

SMILES: CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(s3)-c3cccnc3)nc2c1

InChI Key: InChIKey=DQTBORZYKZITIA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Homo sapiens (Human))	BDBM26839 (N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(s3)-c3cccnc3)nc2c1 Show InChI InChI=1S/C28H24N6O3S/c1-33(27(37)18-6-3-2-4-7-18)20-9-10-22-21(16-20)31-28(34(22)15-13-25(29)35)32-26(36)24-12-11-23(38-24)19-8-5-14-30-17-19/h2-12,14,16-17H,13,15H2,1H3,(H2,29,35)(H,31,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 19: 773-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.028 BindingDB Entry DOI: 10.7270/Q2736P62
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM26839 (N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(s3)-c3cccnc3)nc2c1 Show InChI InChI=1S/C28H24N6O3S/c1-33(27(37)18-6-3-2-4-7-18)20-9-10-22-21(16-20)31-28(34(22)15-13-25(29)35)32-26(36)24-12-11-23(38-24)19-8-5-14-30-17-19/h2-12,14,16-17H,13,15H2,1H3,(H2,29,35)(H,31,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.0	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 19: 773-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.028 BindingDB Entry DOI: 10.7270/Q2736P62
					More data for this Ligand-Target Pair