BDBM268629 US9718825, Example 26
SMILES: Fc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(cc1)-c1nc(Oc2cccnc2)c2cn[nH]c2n1
InChI Key: InChIKey=SIABLCIESZGUCL-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human)) | BDBM268629 (US9718825, Example 26) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1.20 | n/a | n/a | n/a | n/a | 7.4 | n/a |
SANOFI US Patent | Assay Description The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t... | US Patent US9718825 (2017) BindingDB Entry DOI: 10.7270/Q2VM4F82 | |||||||||||
More data for this Ligand-Target Pair |