BDBM26863 2-aminobenzimidazole with trans-stilbene, 8g::N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoylethyl)-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene]-5-[(E)-2-(pyridin-2-yl)ethenyl]thiophene-2-carboxamide

SMILES: CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(C=Cc4ccccn4)s3)nc2c1

InChI Key: InChIKey=BRNRCSOSJKNQDM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Homo sapiens (Human))	BDBM26863 (2-aminobenzimidazole with trans-stilbene, 8g | N-[...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(C=Cc4ccccn4)s3)nc2c1 |w:28.28| Show InChI InChI=1S/C30H26N6O3S/c1-35(29(39)20-7-3-2-4-8-20)22-11-14-25-24(19-22)33-30(36(25)18-16-27(31)37)34-28(38)26-15-13-23(40-26)12-10-21-9-5-6-17-32-21/h2-15,17,19H,16,18H2,1H3,(H2,31,37)(H,33,34,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 18: 6218-21 (2008) Article DOI: 10.1016/j.bmcl.2008.09.098 BindingDB Entry DOI: 10.7270/Q23B5XFW
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM26863 (2-aminobenzimidazole with trans-stilbene, 8g | N-[...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(C=Cc4ccccn4)s3)nc2c1 |w:28.28| Show InChI InChI=1S/C30H26N6O3S/c1-35(29(39)20-7-3-2-4-8-20)22-11-14-25-24(19-22)33-30(36(25)18-16-27(31)37)34-28(38)26-15-13-23(40-26)12-10-21-9-5-6-17-32-21/h2-15,17,19H,16,18H2,1H3,(H2,31,37)(H,33,34,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	7.0	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 18: 6218-21 (2008) Article DOI: 10.1016/j.bmcl.2008.09.098 BindingDB Entry DOI: 10.7270/Q23B5XFW
					More data for this Ligand-Target Pair