BDBM269008 US9718825, Example 451
SMILES: CCOc1nc(nc2[nH]nc(N)c12)-c1ccc(NS(=O)(=O)c2cc(Cl)c(F)cc2F)cc1
InChI Key: InChIKey=UQIJJVCZNWROFR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human)) | BDBM269008 (US9718825, Example 451) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | 7.4 | n/a |
SANOFI US Patent | Assay Description The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t... | US Patent US9718825 (2017) BindingDB Entry DOI: 10.7270/Q2VM4F82 | |||||||||||
More data for this Ligand-Target Pair |