BDBM269092 US9718825, Example 537

SMILES: Clc1ccc(Cl)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1ncc2c(NC(=O)C3CC3)n[nH]c2n1

InChI Key: InChIKey=HSNYDGCJBNNVMH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 269092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM269092 (US9718825, Example 537) Show SMILES Clc1ccc(Cl)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1ncc2c(NC(=O)C3CC3)n[nH]c2n1 Show InChI InChI=1S/C21H16Cl2N6O3S/c22-13-5-8-16(23)17(9-13)33(31,32)29-14-6-3-11(4-7-14)18-24-10-15-19(25-18)27-28-20(15)26-21(30)12-1-2-12/h3-10,12,29H,1-2H2,(H2,24,25,26,27,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.4	n/a
SANOFI US Patent					Assay Description The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...				US Patent US9718825 (2017) BindingDB Entry DOI: 10.7270/Q2VM4F82
					More data for this Ligand-Target Pair