BDBM269441 (E)-3-(4-((6-hydroxy-2- (2-((2-methyl-2H- tetrazol-5- yl)methyl)phenyl)benzo [b]thiophen-3- yl)oxy)phenyl)acrylic acid::US10058534, 96

SMILES: Cn1nnc(Cc2ccccc2-c2sc3cc(O)ccc3c2Oc2ccc(\C=C\C(O)=O)cc2)n1

InChI Key: InChIKey=NZTOUEOBTSJJHI-MDWZMJQESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM269441 ((E)-3-(4-((6-hydroxy-2- (2-((2-methyl-2H- tetrazol...) Show SMILES Cn1nnc(Cc2ccccc2-c2sc3cc(O)ccc3c2Oc2ccc(\C=C\C(O)=O)cc2)n1 Show InChI InChI=1S/C26H20N4O4S/c1-30-28-23(27-29-30)14-17-4-2-3-5-20(17)26-25(21-12-9-18(31)15-22(21)35-26)34-19-10-6-16(7-11-19)8-13-24(32)33/h2-13,15,31H,14H2,1H3,(H,32,33)/b13-8+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...				US Patent US10058534 (2018) BindingDB Entry DOI: 10.7270/Q2M32XSG
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM269441 ((E)-3-(4-((6-hydroxy-2- (2-((2-methyl-2H- tetrazol...) Show SMILES Cn1nnc(Cc2ccccc2-c2sc3cc(O)ccc3c2Oc2ccc(\C=C\C(O)=O)cc2)n1 Show InChI InChI=1S/C26H20N4O4S/c1-30-28-23(27-29-30)14-17-4-2-3-5-20(17)26-25(21-12-9-18(31)15-22(21)35-26)34-19-10-6-16(7-11-19)8-13-24(32)33/h2-13,15,31H,14H2,1H3,(H,32,33)/b13-8+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	212	n/a	n/a	n/a	n/a	5.1	37
Novartis AG US Patent					Assay Description The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...				US Patent US10058534 (2018) BindingDB Entry DOI: 10.7270/Q2M32XSG
					More data for this Ligand-Target Pair