BDBM269451 (E)-3-(4-(2-(4,5- dimethyl-4H-1,2,4- triazol-3- yl)vinyl)phenoxy)-2-(4- fluoro-2- methylphenyl)benzo[b] thiophen-6-ol::US10058534, 106

SMILES: Cc1nnc(\C=C\c2ccc(Oc3c(sc4cc(O)ccc34)-c3ccc(F)cc3C)cc2)n1C

InChI Key: InChIKey=UAHNJYOELTVWCI-AWNIVKPZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM269451 ((E)-3-(4-(2-(4,5- dimethyl-4H-1,2,4- triazol-3- yl...) Show SMILES Cc1nnc(\C=C\c2ccc(Oc3c(sc4cc(O)ccc34)-c3ccc(F)cc3C)cc2)n1C Show InChI InChI=1S/C27H22FN3O2S/c1-16-14-19(28)7-11-22(16)27-26(23-12-8-20(32)15-24(23)34-27)33-21-9-4-18(5-10-21)6-13-25-30-29-17(2)31(25)3/h4-15,32H,1-3H3/b13-6+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...				US Patent US10058534 (2018) BindingDB Entry DOI: 10.7270/Q2M32XSG
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM269451 ((E)-3-(4-(2-(4,5- dimethyl-4H-1,2,4- triazol-3- yl...) Show SMILES Cc1nnc(\C=C\c2ccc(Oc3c(sc4cc(O)ccc34)-c3ccc(F)cc3C)cc2)n1C Show InChI InChI=1S/C27H22FN3O2S/c1-16-14-19(28)7-11-22(16)27-26(23-12-8-20(32)15-24(23)34-27)33-21-9-4-18(5-10-21)6-13-25-30-29-17(2)31(25)3/h4-15,32H,1-3H3/b13-6+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	5.1	37
Novartis AG US Patent					Assay Description The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...				US Patent US10058534 (2018) BindingDB Entry DOI: 10.7270/Q2M32XSG
					More data for this Ligand-Target Pair