BDBM269458 (E)-2-(4-((6-hydroxy-2- (2- isopropylphenyl)benzo [b]thiophen-3- yl)oxy)benzylidene) butanoic acid::US10058534, 113

SMILES: CC\C(=C/c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2C(C)C)cc1)C(O)=O

InChI Key: InChIKey=BARZCAWLKLVINJ-XDJHFCHBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM269458 ((E)-2-(4-((6-hydroxy-2- (2- isopropylphenyl)benzo ...) Show SMILES CC\C(=C/c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2C(C)C)cc1)C(O)=O Show InChI InChI=1S/C28H26O4S/c1-4-19(28(30)31)15-18-9-12-21(13-10-18)32-26-24-14-11-20(29)16-25(24)33-27(26)23-8-6-5-7-22(23)17(2)3/h5-17,29H,4H2,1-3H3,(H,30,31)/b19-15+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...				US Patent US10058534 (2018) BindingDB Entry DOI: 10.7270/Q2M32XSG
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM269458 ((E)-2-(4-((6-hydroxy-2- (2- isopropylphenyl)benzo ...) Show SMILES CC\C(=C/c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2C(C)C)cc1)C(O)=O Show InChI InChI=1S/C28H26O4S/c1-4-19(28(30)31)15-18-9-12-21(13-10-18)32-26-24-14-11-20(29)16-25(24)33-27(26)23-8-6-5-7-22(23)17(2)3/h5-17,29H,4H2,1-3H3,(H,30,31)/b19-15+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62	n/a	n/a	n/a	n/a	5.1	37
Novartis AG US Patent					Assay Description The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...				US Patent US10058534 (2018) BindingDB Entry DOI: 10.7270/Q2M32XSG
					More data for this Ligand-Target Pair