BDBM2704 3-[8-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]indol-11-yl]-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::Bisindolylmaleimide deriv. 9f

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2c3CCC(CN)CCn3c3ccccc23)c2ccccc12

InChI Key: InChIKey=KHZQIBLXYBPFAA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM2704 (3-[8-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CCC(CN)CCn3c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C27H26N4O2/c1-30-15-19(17-6-2-4-8-20(17)30)24-25(27(33)29-26(24)32)23-18-7-3-5-9-21(18)31-13-12-16(14-28)10-11-22(23)31/h2-9,15-16H,10-14,28H2,1H3,(H,29,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	8.5	37
Roche Products Limited					Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein Kinase C (Rattus norvegicus (rat))	BDBM2704 (3-[8-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CCC(CN)CCn3c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C27H26N4O2/c1-30-15-19(17-6-2-4-8-20(17)30)24-25(27(33)29-26(24)32)23-18-7-3-5-9-21(18)31-13-12-16(14-28)10-11-22(23)31/h2-9,15-16H,10-14,28H2,1H3,(H,29,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16.5	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair