null

SMILES: CC[C@@H](Nc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)c1ccccc1

InChI Key: InChIKey=ZTUABMSJXUHFJK-RXVAYIKUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 270572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270572 (N6-((S)-(1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC[C@@H](Nc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)c1ccccc1 |r| Show InChI InChI=1S/C29H28FN7/c1-2-25(19-6-4-3-5-7-19)34-29-24-16-22(12-15-26(24)31-18-32-29)33-28(20-8-10-21(30)11-9-20)27-17-37(36-35-27)23-13-14-23/h3-12,15-18,23,25,28,33H,2,13-14H2,1H3,(H,31,32,34)/t25-,28?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270572 (N6-((S)-(1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC[C@@H](Nc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)c1ccccc1 |r| Show InChI InChI=1S/C29H28FN7/c1-2-25(19-6-4-3-5-7-19)34-29-24-16-22(12-15-26(24)31-18-32-29)33-28(20-8-10-21(30)11-9-20)27-17-37(36-35-27)23-13-14-23/h3-12,15-18,23,25,28,33H,2,13-14H2,1H3,(H,31,32,34)/t25-,28?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	796	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270572 (N6-((S)-(1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC[C@@H](Nc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)c1ccccc1 |r| Show InChI InChI=1S/C29H28FN7/c1-2-25(19-6-4-3-5-7-19)34-29-24-16-22(12-15-26(24)31-18-32-29)33-28(20-8-10-21(30)11-9-20)27-17-37(36-35-27)23-13-14-23/h3-12,15-18,23,25,28,33H,2,13-14H2,1H3,(H,31,32,34)/t25-,28?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270572 (N6-((S)-(1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC[C@@H](Nc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)c1ccccc1 |r| Show InChI InChI=1S/C29H28FN7/c1-2-25(19-6-4-3-5-7-19)34-29-24-16-22(12-15-26(24)31-18-32-29)33-28(20-8-10-21(30)11-9-20)27-17-37(36-35-27)23-13-14-23/h3-12,15-18,23,25,28,33H,2,13-14H2,1H3,(H,31,32,34)/t25-,28?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	796	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair