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BDBM27122 2-[1-(4-cyanophenyl)piperidin-4-yl]-1H-1,3-benzodiazole-4-carboxamide::cyclic amine-containing benzimidazole carboxamide, 10e

SMILES: NC(=O)c1cccc2nc([nH]c12)C1CCN(CC1)c1ccc(cc1)C#N

InChI Key: InChIKey=VZMBLEKOYWPSPQ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27122   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM27122
PNG
(2-[1-(4-cyanophenyl)piperidin-4-yl]-1H-1,3-benzodi...)
Show SMILES NC(=O)c1cccc2nc([nH]c12)C1CCN(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C20H19N5O/c21-12-13-4-6-15(7-5-13)25-10-8-14(9-11-25)20-23-17-3-1-2-16(19(22)26)18(17)24-20/h1-7,14H,8-11H2,(H2,22,26)(H,23,24)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
3n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...


Bioorg Med Chem 16: 6965-75 (2008)


Article DOI: 10.1016/j.bmc.2008.05.044
BindingDB Entry DOI: 10.7270/Q2JD4V3X
More data for this
Ligand-Target Pair