BDBM27134 2-(3-methylazetidin-3-yl)-1H-1,3-benzodiazole-4-carboxamide::benzimidazole carboxamide, 2a

SMILES: CC1(CNC1)c1nc2cccc(C(N)=O)c2[nH]1

InChI Key: InChIKey=PRYWBWSMHQZWSL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27134 (2-(3-methylazetidin-3-yl)-1H-1,3-benzodiazole-4-ca...) Show SMILES CC1(CNC1)c1nc2cccc(C(N)=O)c2[nH]1 Show InChI InChI=1S/C12H14N4O/c1-12(5-14-6-12)11-15-8-4-2-3-7(10(13)17)9(8)16-11/h2-4,14H,5-6H2,1H3,(H2,13,17)(H,15,16)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4	-11.3	n/a	n/a	n/a	n/a	n/a	8.0	22
Abbott Laboratories					Assay Description PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...				J Med Chem 52: 514-23 (2009) Article DOI: 10.1021/jm801171j BindingDB Entry DOI: 10.7270/Q2DN43CK
					More data for this Ligand-Target Pair