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SMILES: Cn1c2cc(Oc3ccc(F)cc3Cl)ccc2c(O)c(C(=O)NCC(O)=O)c1=O

InChI Key: InChIKey=NNINGKKFYJLFGC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 271481   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hypoxia-inducible factor 1-alpha


(Homo sapiens (Human))		BDBM271481
PNG
(2-(7-(2-chloro-4-fluorophenoxy)-4-hydroxy-1-methyl...)
Show SMILES Cn1c2cc(Oc3ccc(F)cc3Cl)ccc2c(O)c(C(=O)NCC(O)=O)c1=O
Show InChI InChI=1S/C19H14ClFN2O6/c1-23-13-7-10(29-14-5-2-9(21)6-12(14)20)3-4-11(13)17(26)16(19(23)28)18(27)22-8-15(24)25/h2-7,26H,8H2,1H3,(H,22,27)(H,24,25)
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US Patent
n/an/an/an/a 1.51E+3n/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
The activities of compounds of the invention in inducing erythropoietin (EPO) production were assessed by using human live cancer cell strain Hep3B (...

US Patent US10065928 (2018)


BindingDB Entry DOI: 10.7270/Q2DB83WQ
More data for this
Ligand-Target Pair