BDBM271938 US10065941, Compound R-256::US9732060, Compound R-256

SMILES: NC(=O)NC(=O)Cn1c(=O)[nH]\c(=N/c2ccc(Oc3ccccn3)cc2)n(Cc2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=HRZSXWMCUMJBGW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 271938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM271938 (US10065941, Compound R-256 | US9732060, Compound R...) Show SMILES NC(=O)NC(=O)Cn1c(=O)[nH]\c(=N/c2ccc(Oc3ccccn3)cc2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C24H20ClN7O5/c25-16-6-4-15(5-7-16)13-31-22(30-23(35)32(24(31)36)14-19(33)29-21(26)34)28-17-8-10-18(11-9-17)37-20-3-1-2-12-27-20/h1-12H,13-14H2,(H,28,30,35)(H3,26,29,33,34)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...				US Patent US9732060 (2017) BindingDB Entry DOI: 10.7270/Q2ZC8506
					More data for this Ligand-Target Pair
p2x3 (Homo sapiens (Human))	BDBM271938 (US10065941, Compound R-256 | US9732060, Compound R...) Show SMILES NC(=O)NC(=O)Cn1c(=O)[nH]\c(=N/c2ccc(Oc3ccccn3)cc2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C24H20ClN7O5/c25-16-6-4-15(5-7-16)13-31-22(30-23(35)32(24(31)36)14-19(33)29-21(26)34)28-17-8-10-18(11-9-17)37-20-3-1-2-12-27-20/h1-12H,13-14H2,(H,28,30,35)(H3,26,29,33,34)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...				US Patent US10065941 (2018) BindingDB Entry DOI: 10.7270/Q28P62J8
					More data for this Ligand-Target Pair