BDBM272067 (S)-5-(3-Fluoro-2-methylphenyl)-l-(2-fluorophenyl)- N-hydroxy-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-5- carboxamide::US10065948, 3::US10457675, Example 3

SMILES: Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccccc1F)C(=O)NO

InChI Key: InChIKey=IXCFRNUMYXMRAI-FQEVSTJZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272067 ((S)-5-(3-Fluoro-2-methylphenyl)-l-(2-fluorophenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccccc1F)C(=O)NO |r| Show InChI InChI=1S/C20H17F2N3O2/c1-12-14(5-4-7-15(12)21)20(19(26)24-27)9-13-11-23-25(18(13)10-20)17-8-3-2-6-16(17)22/h2-8,11,27H,9-10H2,1H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10457675 (2019) BindingDB Entry DOI: 10.7270/Q22J6F7J
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272067 ((S)-5-(3-Fluoro-2-methylphenyl)-l-(2-fluorophenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccccc1F)C(=O)NO |r| Show InChI InChI=1S/C20H17F2N3O2/c1-12-14(5-4-7-15(12)21)20(19(26)24-27)9-13-11-23-25(18(13)10-20)17-8-3-2-6-16(17)22/h2-8,11,27H,9-10H2,1H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair