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SMILES: Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccc(F)cc1)C(=O)NO

InChI Key: InChIKey=JUXDXYLWGRZWIC-FQEVSTJZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272069 ((S)-5-(3-Fluoro-2-methylphenyl)-1-(4-fluorophenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccc(F)cc1)C(=O)NO |r| Show InChI InChI=1S/C20H17F2N3O2/c1-12-16(3-2-4-17(12)22)20(19(26)24-27)9-13-11-23-25(18(13)10-20)15-7-5-14(21)6-8-15/h2-8,11,27H,9-10H2,1H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10457675 (2019) BindingDB Entry DOI: 10.7270/Q22J6F7J
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272069 ((S)-5-(3-Fluoro-2-methylphenyl)-1-(4-fluorophenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccc(F)cc1)C(=O)NO |r| Show InChI InChI=1S/C20H17F2N3O2/c1-12-16(3-2-4-17(12)22)20(19(26)24-27)9-13-11-23-25(18(13)10-20)15-7-5-14(21)6-8-15/h2-8,11,27H,9-10H2,1H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair