BDBM27211 (2S)-2-acetamido-N,4-dimethyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,7,13-trimethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-yl]pentanamide::Conessine analogue, 13d

SMILES: [H][C@@]1(C)N(C)C[C@]23CC[C@@]4([H])[C@@]([H])(CC=C5C[C@H](CC[C@]45C)N(C)C(=O)[C@H](CC(C)C)NC(C)=O)[C@]2([H])CC[C@]13[H]

InChI Key: InChIKey=YNZJHECUVVZSLB-JDEVNGBYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM27211 ((2S)-2-acetamido-N,4-dimethyl-N-[(1R,2S,5S,6S,9R,1...) Show SMILES [H][C@@]1(C)N(C)C[C@]23CC[C@@]4([H])[C@@]([H])(CC=C5C[C@H](CC[C@]45C)N(C)C(=O)[C@H](CC(C)C)NC(C)=O)[C@]2([H])CC[C@]13[H] |r,t:14| Show InChI InChI=1S/C31H51N3O2/c1-19(2)16-28(32-21(4)35)29(36)34(7)23-12-14-30(5)22(17-23)8-9-24-26(30)13-15-31-18-33(6)20(3)25(31)10-11-27(24)31/h8,19-20,23-28H,9-18H2,1-7H3,(H,32,35)/t20-,23-,24+,25+,26-,27-,28-,30-,31-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.62	-12.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Abbott Laboratories					Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...				J Med Chem 51: 5423-30 (2008) Article DOI: 10.1021/jm8003625 BindingDB Entry DOI: 10.7270/Q21G0JK0
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM27211 ((2S)-2-acetamido-N,4-dimethyl-N-[(1R,2S,5S,6S,9R,1...) Show SMILES [H][C@@]1(C)N(C)C[C@]23CC[C@@]4([H])[C@@]([H])(CC=C5C[C@H](CC[C@]45C)N(C)C(=O)[C@H](CC(C)C)NC(C)=O)[C@]2([H])CC[C@]13[H] |r,t:14| Show InChI InChI=1S/C31H51N3O2/c1-19(2)16-28(32-21(4)35)29(36)34(7)23-12-14-30(5)22(17-23)8-9-24-26(30)13-15-31-18-33(6)20(3)25(31)10-11-27(24)31/h8,19-20,23-28H,9-18H2,1-7H3,(H,32,35)/t20-,23-,24+,25+,26-,27-,28-,30-,31-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	6.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...				J Med Chem 51: 5423-30 (2008) Article DOI: 10.1021/jm8003625 BindingDB Entry DOI: 10.7270/Q21G0JK0
					More data for this Ligand-Target Pair