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SMILES: Cc1c(F)cccc1[C@]1(Cc2nc(sc2C1)-c1ccc(F)cn1)C(=O)NO

InChI Key: InChIKey=DTQZSNICTXHRFE-LJQANCHMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272154 ((R)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(5- fl...) Show SMILES Cc1c(F)cccc1[C@]1(Cc2nc(sc2C1)-c1ccc(F)cn1)C(=O)NO |r| Show InChI InChI=1S/C19H15F2N3O2S/c1-10-12(3-2-4-13(10)21)19(18(25)24-26)7-15-16(8-19)27-17(23-15)14-6-5-11(20)9-22-14/h2-6,9,26H,7-8H2,1H3,(H,24,25)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10457675 (2019) BindingDB Entry DOI: 10.7270/Q22J6F7J
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272154 ((R)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(5- fl...) Show SMILES Cc1c(F)cccc1[C@]1(Cc2nc(sc2C1)-c1ccc(F)cn1)C(=O)NO |r| Show InChI InChI=1S/C19H15F2N3O2S/c1-10-12(3-2-4-13(10)21)19(18(25)24-26)7-15-16(8-19)27-17(23-15)14-6-5-11(20)9-22-14/h2-6,9,26H,7-8H2,1H3,(H,24,25)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair